2ae9: Difference between revisions

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==Solution Structure of the theta subunit of DNA polymerase III from E. coli==
==Solution Structure of the theta subunit of DNA polymerase III from E. coli==
<StructureSection load='2ae9' size='340' side='right'caption='[[2ae9]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='2ae9' size='340' side='right'caption='[[2ae9]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ae9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AE9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AE9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ae9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AE9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AE9 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">holE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ae9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ae9 OCA], [https://pdbe.org/2ae9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ae9 RCSB], [https://www.ebi.ac.uk/pdbsum/2ae9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ae9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ae9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ae9 OCA], [https://pdbe.org/2ae9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ae9 RCSB], [https://www.ebi.ac.uk/pdbsum/2ae9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ae9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/HOLE_ECOLI HOLE_ECOLI]] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The exact function of the theta subunit is unknown.  
[https://www.uniprot.org/uniprot/HOLE_ECOLI HOLE_ECOLI] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The exact function of the theta subunit is unknown.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 2ae9" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2ae9" style="background-color:#fffaf0;"></div>
==See Also==
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Derose, E F]]
[[Category: Derose EF]]
[[Category: Kirby, T W]]
[[Category: Kirby TW]]
[[Category: Li, D]]
[[Category: Li D]]
[[Category: London, R E]]
[[Category: London RE]]
[[Category: Mueller, G A]]
[[Category: Mueller GA]]
[[Category: Schaaper, R M]]
[[Category: Schaaper RM]]
[[Category: Helice]]
[[Category: All helical]]
[[Category: Transferase]]

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