1ysx: Difference between revisions

<StructureSection load='1ysx' size='340' side='right'caption='[[1ysx]]' scene=''>

<table><tr><td colspan='2'>[[1ysx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YSX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YSX FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4EB:4-({2-[(2,4-DIMETHYLPHENYL)SULFANYL]ETHYL}AMINO)-N-[(4-FLUORO-1,1-BIPHENYL-4-YL)CARBONYL]-3-NITROBENZENESULFONAMIDE'>4EB</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ysx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ysx OCA], [https://pdbe.org/1ysx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ysx RCSB], [https://www.ebi.ac.uk/pdbsum/1ysx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ysx ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[https://omim.org/entry/103600 103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>  

[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>  

     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ys/1ysx_consurf.spt"</scriptWhenChecked>

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ysx ConSurf].

*[[Albumin 3D structures|Albumin 3D structures]]

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Armstrong RC]]

[[Category: Augeri DJ]]

[[Category: Belli BA]]

[[Category: Bruncko M]]

[[Category: Deckwerth TL]]

[[Category: Dinges J]]

[[Category: Elmore SW]]

[[Category: Fesik SW]]

[[Category: Hajduk PJ]]

[[Category: Joseph MK]]

[[Category: Kitada S]]

[[Category: Korsmeyer SJ]]

[[Category: Kunzer AR]]

[[Category: Letai A]]

[[Category: Li C]]

[[Category: Mitten MJ]]

[[Category: Nettesheim DG]]

[[Category: Ng S]]

[[Category: Nimmer PM]]

[[Category: O'Connor JM]]

[[Category: Oleksijew A]]

[[Category: Oltersdorf T]]

[[Category: Petros AM]]

[[Category: Reed JC]]

[[Category: Rosenberg SH]]

[[Category: Shen W]]

[[Category: Shoemaker AR]]

[[Category: Tahir SK]]

[[Category: Thompson CB]]

[[Category: Tomaselli KJ]]

[[Category: Wang B]]

[[Category: Wendt MD]]

[[Category: Zhang H]]