1y3h: Difference between revisions
No edit summary |
No edit summary |
||
| (2 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal Structure of Inorganic Polyphosphate/ATP-NAD kinase from Mycobacterium tuberculosis== | ==Crystal Structure of Inorganic Polyphosphate/ATP-NAD kinase from Mycobacterium tuberculosis== | ||
<StructureSection load='1y3h' size='340' side='right' caption='[[1y3h]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='1y3h' size='340' side='right'caption='[[1y3h]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1y3h]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1y3h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y3H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y3H FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y3h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y3h OCA], [https://pdbe.org/1y3h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y3h RCSB], [https://www.ebi.ac.uk/pdbsum/1y3h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y3h ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/NADK_MYCTU NADK_MYCTU] Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. It can use ATP and other nucleoside triphosphates as well as inorganic polyphosphate (poly(P)) as a source of phosphorus.[HAMAP-Rule:MF_00361]<ref>PMID:11006082</ref> <ref>PMID:15182203</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 37: | Line 35: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Hashimoto | [[Category: Large Structures]] | ||
[[Category: Maruyama | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Mikami | [[Category: Hashimoto W]] | ||
[[Category: Momma | [[Category: Maruyama Y]] | ||
[[Category: Mori | [[Category: Mikami B]] | ||
[[Category: Murata | [[Category: Momma K]] | ||
[[Category: Yamasaki | [[Category: Mori S]] | ||
[[Category: Kawai | [[Category: Murata K]] | ||
[[Category: Yamasaki M]] | |||
[[Category: Kawai S]] | |||