1xsa: Difference between revisions

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OCA

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 ==Structure of the nudix enzyme AP4A hydrolase from homo sapiens (E63A mutant)==
-<StructureSection load='1xsa' size='340' side='right' caption='[[1xsa]], [[NMR_Ensembles_of_Models | 33 NMR models]]' scene=''>
+<StructureSection load='1xsa' size='340' side='right'caption='[[1xsa]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1xsa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XSA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XSA FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1xsa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XSA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XSA FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xsb|1xsb]], [[1xsc|1xsc]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Bis(5'-nucleosyl)-tetraphosphatase_(asymmetrical) Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.17 3.6.1.17] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xsa OCA], [https://pdbe.org/1xsa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xsa RCSB], [https://www.ebi.ac.uk/pdbsum/1xsa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xsa ProSAT]</span></td></tr>
-<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xsa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xsa RCSB], [http://www.ebi.ac.uk/pdbsum/1xsa PDBsum]</span></td></tr>
+</table>
-<table>
+== Function ==
+[https://www.uniprot.org/uniprot/AP4A_HUMAN AP4A_HUMAN] Asymmetrically hydrolyzes Ap4A to yield AMP and ATP. Plays a major role in maintaining homeostasis.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xs/1xsa_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xs/1xsa_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xsa ConSurf].
 <div style="clear:both"></div>
 <div style="background-color:#fffaf0;">
@@ Line 25: / Line 27: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 1xsa" style="background-color:#fffaf0;"></div>
 == References ==
 <references/>
@@ Line 30: / Line 33: @@
 </StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Buyya, S.]]
+[[Category: Large Structures]]
-[[Category: Gayler, K R.]]
+[[Category: Buyya S]]
-[[Category: Gooley, P R.]]
+[[Category: Gayler KR]]
-[[Category: Gunawardana, D.]]
+[[Category: Gooley PR]]
-[[Category: McLennan, A G.]]
+[[Category: Gunawardana D]]
-[[Category: Swarbrick, J D.]]
+[[Category: McLennan AG]]
-[[Category: Alpha-beta]]
+[[Category: Swarbrick JD]]
-[[Category: Human ap4a hydrolase]]
-[[Category: Hydrolase]]
-[[Category: Nudix enzyme]]