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{{Large structure}}
 
==NMR Solution Structure of the PRO Form of Human Matrilysin (proMMP-7)==
==NMR Solution Structure of the PRO Form of Human Matrilysin (proMMP-7)==
<StructureSection load='2mze' size='340' side='right' caption='[[2mze]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2mze' size='340' side='right'caption='[[2mze]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2mze]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MZE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MZE FirstGlance]. <br>
<table><tr><td colspan='2'>[[2mze]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MZE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MZE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2y6d|2y6d]], [[2y6c|2y6c]], [[1mmp|1mmp]], [[1mmq|1mmq]], [[1mmr|1mmr]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MMP7, MPSL1, PUMP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mze OCA], [https://pdbe.org/2mze PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mze RCSB], [https://www.ebi.ac.uk/pdbsum/2mze PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mze ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Matrilysin Matrilysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.23 3.4.24.23] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mze OCA], [http://pdbe.org/2mze PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mze RCSB], [http://www.ebi.ac.uk/pdbsum/2mze PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2mze ProSAT]</span></td></tr>
</table>
</table>
{{Large structure}}
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MMP7_HUMAN MMP7_HUMAN]] Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.<ref>PMID:2550050</ref>
[https://www.uniprot.org/uniprot/MMP7_HUMAN MMP7_HUMAN] Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.<ref>PMID:2550050</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 2mze" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2mze" style="background-color:#fffaf0;"></div>
==See Also==
*[[Matrix metalloproteinase 3D structures|Matrix metalloproteinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Matrilysin]]
[[Category: Large Structures]]
[[Category: Doren, S R.Van]]
[[Category: Fulcher YG]]
[[Category: Fulcher, Y G]]
[[Category: Prior SH]]
[[Category: Prior, S H]]
[[Category: Van Doren SR]]
[[Category: Hydrolase]]
[[Category: Metalloenzyme]]
[[Category: Zymogen]]

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