2mjc: Difference between revisions

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-'''Unreleased structure'''
-The entry 2mjc is ON HOLD  until Jan 07 2016
+==Zn-binding domain of eukaryotic translation initiation factor 3, subunit G==
+<StructureSection load='2mjc' size='340' side='right'caption='[[2mjc]]' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2mjc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MJC FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mjc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mjc OCA], [https://pdbe.org/2mjc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mjc RCSB], [https://www.ebi.ac.uk/pdbsum/2mjc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mjc ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/EIF3G_HUMAN EIF3G_HUMAN] Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.
-Authors: Al-Abdul-Wahid, M., Menade, M., Xie, J., Kozlov, G., Gehring, K.
+==See Also==
+*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]]
-Description: Zn-binding domain of eukaryotic translation initiation factor 3, subunit G
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Kozlov, G]]
+[[Category: Homo sapiens]]
-[[Category: Gehring, K]]
+[[Category: Large Structures]]
-[[Category: Xie, J]]
+[[Category: Al-Abdul-Wahid M]]
-[[Category: Menade, M]]
+[[Category: Gehring K]]
-[[Category: Al-Abdul-Wahid, M]]
+[[Category: Kozlov G]]
+[[Category: Menade M]]
+[[Category: Xie J]]