2m5e: Difference between revisions

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 ==Structure of the C-domain of Calcium-saturated Calmodulin bound to the IQ motif of NaV1.2==
-<StructureSection load='2m5e' size='340' side='right' caption='[[2m5e]], [[NMR_Ensembles_of_Models | 21 NMR models]]' scene=''>
+<StructureSection load='2m5e' size='340' side='right'caption='[[2m5e]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2m5e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat] and [http://en.wikipedia.org/wiki/Parte Parte]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M5E FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2m5e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Paramecium_tetraurelia Paramecium tetraurelia] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M5E FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2kxw|2kxw]], [[1exr|1exr]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CAM, GSPATT00015825001 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5888 PARTE]), Scn2a, Scn2a1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5e OCA], [https://pdbe.org/2m5e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m5e RCSB], [https://www.ebi.ac.uk/pdbsum/2m5e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m5e ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5e OCA], [http://pdbe.org/2m5e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2m5e RCSB], [http://www.ebi.ac.uk/pdbsum/2m5e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2m5e ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/CALM_PARTE CALM_PARTE]] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. [[http://www.uniprot.org/uniprot/SCN2A_RAT SCN2A_RAT]] Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
+[https://www.uniprot.org/uniprot/CALM_PARTE CALM_PARTE] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 22: / Line 21: @@
 ==See Also==
-*[[Calmodulin|Calmodulin]]
+*[[Calmodulin 3D structures|Calmodulin 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Buffalo rat]]
+[[Category: Large Structures]]
-[[Category: Parte]]
+[[Category: Paramecium tetraurelia]]
-[[Category: Feldkamp, M D]]
+[[Category: Rattus norvegicus]]
-[[Category: Fowler, C A]]
+[[Category: Feldkamp MD]]
-[[Category: Shea, M A]]
+[[Category: Fowler CA]]
-[[Category: Yu, L]]
+[[Category: Shea MA]]
-[[Category: Calcium binding protein]]
+[[Category: Yu L]]
-[[Category: Calcium binding protein-metal transport complex]]
-[[Category: Calcium-binding protein-metal transport complex]]
-[[Category: Ef-hand]]
-[[Category: Ion channel gating]]
-[[Category: Iq motif]]
-[[Category: Metal binding]]
-[[Category: Metal transport]]
-[[Category: Nav1 2]]
-[[Category: Neuronal peptide]]
-[[Category: Sodium channel]]
-[[Category: Voltage dependent]]
-[[Category: Voltage gated]]