2luo: Difference between revisions

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 ==NMR solution structure of apo-MptpA==
-<StructureSection load='2luo' size='340' side='right' caption='[[2luo]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+<StructureSection load='2luo' size='340' side='right'caption='[[2luo]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2luo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LUO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LUO FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2luo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LUO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LUO FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1u2p|1u2p]], [[1u2q|1u2q]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ptpA, Rv2234, MT2293, MTCY427.15 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2luo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2luo OCA], [https://pdbe.org/2luo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2luo RCSB], [https://www.ebi.ac.uk/pdbsum/2luo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2luo ProSAT]</span></td></tr>
-<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
+</table>
-<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2luo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2luo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2luo RCSB], [http://www.ebi.ac.uk/pdbsum/2luo PDBsum]</span></td></tr>
+== Function ==
-<table>
+[https://www.uniprot.org/uniprot/PTPA_MYCTU PTPA_MYCTU] Mediates host-pathogen interaction and interferes with vesicular trafficking in the infected macrophage. Inhibits host phagolysosomal fusion in M.tuberculosis-infected macrophages to promote bacteria survival. Dephosphorylates host VPS33B protein, which induces a block of the host phagosome maturation within macrophage cells. Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 16: / Line 17: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 2luo" style="background-color:#fffaf0;"></div>
 ==See Also==
-*[[Tyrosine phosphatase|Tyrosine phosphatase]]
+*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
+[[Category: Large Structures]]
 [[Category: Mycobacterium tuberculosis]]
-[[Category: Protein-tyrosine-phosphatase]]
+[[Category: Jonker HRA]]
-[[Category: Jonker, H R.A.]]
+[[Category: Loehr F]]
-[[Category: Loehr, F.]]
+[[Category: Richter C]]
-[[Category: Richter, C.]]
+[[Category: Saxena K]]
-[[Category: Saxena, K.]]
+[[Category: Schwalbe H]]
-[[Category: Schwalbe, H.]]
+[[Category: Sreeramulu S]]
-[[Category: Sreeramulu, S.]]
+[[Category: Stehle T]]
-[[Category: Stehle, T.]]
-[[Category: Hydrolase]]
-[[Category: Low molecular weight tyrosine phosphatase]]
-[[Category: Mptpa]]