2lp5: Difference between revisions

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==Native Structure of the Fyn SH3 A39V/N53P/V55L==
==Native Structure of the Fyn SH3 A39V/N53P/V55L==
<StructureSection load='2lp5' size='340' side='right' caption='[[2lp5]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='2lp5' size='340' side='right'caption='[[2lp5]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2lp5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LP5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LP5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2lp5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LP5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LP5 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1shf|1shf]], [[3cqt|3cqt]], [[2l2p|2l2p]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FYN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 Gallus gallus])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lp5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lp5 OCA], [https://pdbe.org/2lp5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lp5 RCSB], [https://www.ebi.ac.uk/pdbsum/2lp5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lp5 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lp5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lp5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lp5 RCSB], [http://www.ebi.ac.uk/pdbsum/2lp5 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FYN_CHICK FYN_CHICK]] Tyrosine-protein kinase implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Role in CNTN1-mediated signaling.<ref>PMID:7496631</ref>
[https://www.uniprot.org/uniprot/FYN_CHICK FYN_CHICK] Tyrosine-protein kinase implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Role in CNTN1-mediated signaling.<ref>PMID:7496631</ref>  
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2lp5" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Tyrosine kinase|Tyrosine kinase]]
*[[Tyrosine kinase 3D structures|Tyrosine kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Large Structures]]
[[Category: Cavalli, A]]
[[Category: Cavalli A]]
[[Category: Kay, L E]]
[[Category: Kay LE]]
[[Category: Neudecker, P]]
[[Category: Neudecker P]]
[[Category: Robustelli, P]]
[[Category: Robustelli P]]
[[Category: Vendruscolo, M]]
[[Category: Vendruscolo M]]
[[Category: Amyloid fibril]]
[[Category: Protein folding intermediate]]
[[Category: Transferase]]

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