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==Solution NMR structure of a helical bundle domain from human E3 ligase HECTD1. Northeast structural genomics consortium (NESG) target HT6305A==
==Solution NMR structure of a helical bundle domain from human E3 ligase HECTD1. Northeast structural genomics consortium (NESG) target HT6305A==
<StructureSection load='2lc3' size='340' side='right' caption='[[2lc3]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2lc3' size='340' side='right'caption='[[2lc3]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2lc3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LC3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LC3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2lc3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LC3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LC3 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HECTD1, KIAA1131 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lc3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lc3 RCSB], [http://www.ebi.ac.uk/pdbsum/2lc3 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lc3 OCA], [https://pdbe.org/2lc3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lc3 RCSB], [https://www.ebi.ac.uk/pdbsum/2lc3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lc3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HECD1_HUMAN HECD1_HUMAN]] Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. May be required for development of the head mesenchyme and neural tube closure (By similarity).  
[https://www.uniprot.org/uniprot/HECD1_HUMAN HECD1_HUMAN] Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. May be required for development of the head mesenchyme and neural tube closure (By similarity).


==See Also==
==See Also==
*[[Ubiquitin protein ligase|Ubiquitin protein ligase]]
*[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C]]
[[Category: Large Structures]]
[[Category: Dhe-Paganon, S]]
[[Category: Arrowsmith C]]
[[Category: Garcia, M]]
[[Category: Dhe-Paganon S]]
[[Category: Houliston, S]]
[[Category: Garcia M]]
[[Category: Lemak, A]]
[[Category: Houliston S]]
[[Category: Montelione, G T]]
[[Category: Lemak A]]
[[Category: Structural genomic]]
[[Category: Montelione GT]]
[[Category: Yee, A]]
[[Category: Yee A]]
[[Category: Helical bundle]]
[[Category: Ligase]]
[[Category: Nesg]]
[[Category: Sgc]]

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