2lc3: Difference between revisions
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==Solution NMR structure of a helical bundle domain from human E3 ligase HECTD1. Northeast structural genomics consortium (NESG) target HT6305A== | |||
<StructureSection load='2lc3' size='340' side='right'caption='[[2lc3]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2lc3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LC3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LC3 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lc3 OCA], [https://pdbe.org/2lc3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lc3 RCSB], [https://www.ebi.ac.uk/pdbsum/2lc3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lc3 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/HECD1_HUMAN HECD1_HUMAN] Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. May be required for development of the head mesenchyme and neural tube closure (By similarity). | |||
==See Also== | |||
*[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith C]] | |||
[[Category: Dhe-Paganon S]] | |||
[[Category: Garcia M]] | |||
[[Category: Houliston S]] | |||
[[Category: Lemak A]] | |||
[[Category: Montelione GT]] | |||
[[Category: Yee A]] |