2kmu: Difference between revisions

No edit summary
No edit summary
 
(One intermediate revision by the same user not shown)
Line 1: Line 1:


==RecQL4 Amino-terminal Domain==
==RecQL4 Amino-terminal Domain==
<StructureSection load='2kmu' size='340' side='right'caption='[[2kmu]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2kmu' size='340' side='right'caption='[[2kmu]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2kmu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KMU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KMU FirstGlance]. <br>
<table><tr><td colspan='2'>[[2kmu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KMU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KMU FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RECQL4, RECQ4 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kmu OCA], [https://pdbe.org/2kmu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kmu RCSB], [https://www.ebi.ac.uk/pdbsum/2kmu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kmu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kmu OCA], [https://pdbe.org/2kmu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kmu RCSB], [https://www.ebi.ac.uk/pdbsum/2kmu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kmu ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[https://www.uniprot.org/uniprot/RECQ4_HUMAN RECQ4_HUMAN]] RAPADILINO syndrome;Baller-Gerold syndrome;Rothmund-Thomson syndrome type 2. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  
[https://www.uniprot.org/uniprot/RECQ4_HUMAN RECQ4_HUMAN] RAPADILINO syndrome;Baller-Gerold syndrome;Rothmund-Thomson syndrome type 2. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/RECQ4_HUMAN RECQ4_HUMAN]] DNA-dependent ATPase. May modulate chromosome segregation.<ref>PMID:15317757</ref>
[https://www.uniprot.org/uniprot/RECQ4_HUMAN RECQ4_HUMAN] DNA-dependent ATPase. May modulate chromosome segregation.<ref>PMID:15317757</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 37: Line 37:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Gorlach, M]]
[[Category: Gorlach M]]
[[Category: Ohlenschlager, O]]
[[Category: Ohlenschlager O]]
[[Category: Pospiech, H]]
[[Category: Pospiech H]]
[[Category: Atp-binding]]
[[Category: Cataract]]
[[Category: Craniosynostosis]]
[[Category: Disease mutation]]
[[Category: Dna-replication]]
[[Category: Dwarfism]]
[[Category: Helicase]]
[[Category: Homeodomain-like]]
[[Category: Hydrolase]]
[[Category: Nucleotide-binding]]
[[Category: Recql4]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA