2bru: Difference between revisions

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-{{Large structure}}
-{{STRUCTURE_2bru|  PDB=2bru  |  SCENE=  }}
-===COMPLEX OF THE DOMAIN I AND DOMAIN III OF ESCHERICHIA COLI TRANSHYDROGENASE===
-==About this Structure==
+==Complex of the domain I and domain III of Escherichia coli transhydrogenase==
-[[2bru]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRU OCA].
+<StructureSection load='2bru' size='340' side='right'caption='[[2bru]]' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2bru]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BRU FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bru OCA], [https://pdbe.org/2bru PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bru RCSB], [https://www.ebi.ac.uk/pdbsum/2bru PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bru ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PNTA_ECOLI PNTA_ECOLI] The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/2bru_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bru ConSurf].
+<div style="clear:both"></div>
+==See Also==
+*[[NAD(P) transhydrogenase 3D structures|NAD(P) transhydrogenase 3D structures]]
+__TOC__
+</StructureSection>
 [[Category: Escherichia coli]]
-[[Category: Johansson, T.]]
+[[Category: Large Structures]]
-[[Category: Karlsson, B G.]]
+[[Category: Johansson T]]
-[[Category: Leckner, J.]]
+[[Category: Karlsson BG]]
-[[Category: Pedersen, A.]]
+[[Category: Leckner J]]
-[[Category: Inner membrane]]
+[[Category: Pedersen A]]
-[[Category: Membrane]]
-[[Category: Nad]]
-[[Category: Nadp]]
-[[Category: Oxidoreductase]]
-[[Category: Paramagnetic nmr]]
-[[Category: Transhydrogenase]]
-[[Category: Transmembrane]]