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==Solution structure of the E.coli RcsC C-terminus (residues 700-949) containing linker region and phosphoreceiver domain==
==Solution structure of the E.coli RcsC C-terminus (residues 700-949) containing linker region and phosphoreceiver domain==
<StructureSection load='2ayx' size='340' side='right'caption='[[2ayx]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2ayx' size='340' side='right'caption='[[2ayx]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ayx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AYX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AYX FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ayx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AYX FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ayy|2ayy]], [[2ayz|2ayz]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rcsC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ayx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ayx OCA], [https://pdbe.org/2ayx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ayx RCSB], [https://www.ebi.ac.uk/pdbsum/2ayx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ayx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ayx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ayx OCA], [http://pdbe.org/2ayx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ayx RCSB], [http://www.ebi.ac.uk/pdbsum/2ayx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ayx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RCSC_ECOLI RCSC_ECOLI]] Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. RcsC has also phosphatase activity. The system controls expression of genes involved in colanic acid capsule synthesis, biofilm formation and cell division.<ref>PMID:10564486</ref> <ref>PMID:11758943</ref> <ref>PMID:11309126</ref> <ref>PMID:11807084</ref> <ref>PMID:13129944</ref> <ref>PMID:14651646</ref>
[https://www.uniprot.org/uniprot/RCSC_ECOLI RCSC_ECOLI] Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. RcsC has also phosphatase activity. The system controls expression of genes involved in colanic acid capsule synthesis, biofilm formation and cell division.<ref>PMID:10564486</ref> <ref>PMID:11758943</ref> <ref>PMID:11309126</ref> <ref>PMID:11807084</ref> <ref>PMID:13129944</ref> <ref>PMID:14651646</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bernhard, F]]
[[Category: Bernhard F]]
[[Category: Dotsch, V]]
[[Category: Dotsch V]]
[[Category: Koglin, A]]
[[Category: Koglin A]]
[[Category: Lohr, F]]
[[Category: Lohr F]]
[[Category: Rogov, V V]]
[[Category: Rogov VV]]
[[Category: Rogova, N Y]]
[[Category: Rogova NY]]
[[Category: Transferase]]
[[Category: Two independent structural domain]]

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