1m3v: Difference between revisions
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==FLIN4: Fusion of the LIM binding domain of Ldb1 and the N-terminal LIM domain of LMO4== | ==FLIN4: Fusion of the LIM binding domain of Ldb1 and the N-terminal LIM domain of LMO4== | ||
<StructureSection load='1m3v' size='340' side='right'caption='[[1m3v | <StructureSection load='1m3v' size='340' side='right'caption='[[1m3v]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1m3v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1m3v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M3V FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m3v OCA], [https://pdbe.org/1m3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m3v RCSB], [https://www.ebi.ac.uk/pdbsum/1m3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m3v ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m3v OCA], [https://pdbe.org/1m3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m3v RCSB], [https://www.ebi.ac.uk/pdbsum/1m3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m3v ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/LDB1_MOUSE LDB1_MOUSE] Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. May play a role in the development of motor neurons. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state.<ref>PMID:8918878</ref> <ref>PMID:8876198</ref> <ref>PMID:9192866</ref> <ref>PMID:9391090</ref> <ref>PMID:16815859</ref> <ref>PMID:9315627</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Deane | [[Category: Deane JE]] | ||
[[Category: Kwan | [[Category: Kwan AHY]] | ||
[[Category: Mackay | [[Category: Mackay JP]] | ||
[[Category: Matthews | [[Category: Matthews JM]] | ||
[[Category: Sum | [[Category: Sum EY]] | ||
[[Category: Visvader | [[Category: Visvader JE]] | ||