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==Solution Structure of the HMG_box Domain of Murine Bobby Sox Homolog==
==Solution Structure of the HMG_box Domain of Murine Bobby Sox Homolog==
<StructureSection load='1wz6' size='340' side='right' caption='[[1wz6]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1wz6' size='340' side='right'caption='[[1wz6]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1wz6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WZ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WZ6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1wz6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WZ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WZ6 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Bbx ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wz6 OCA], [http://pdbe.org/1wz6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wz6 RCSB], [http://www.ebi.ac.uk/pdbsum/1wz6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1wz6 ProSAT], [http://www.topsan.org/Proteins/RSGI/1wz6 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wz6 OCA], [https://pdbe.org/1wz6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wz6 RCSB], [https://www.ebi.ac.uk/pdbsum/1wz6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wz6 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wz6 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BBX_MOUSE BBX_MOUSE]] Transcription factor that is necessary for cell cycle progression from G1 to S phase.<ref>PMID:11680820</ref>
[https://www.uniprot.org/uniprot/BBX_MOUSE BBX_MOUSE] Transcription factor that is necessary for cell cycle progression from G1 to S phase.<ref>PMID:11680820</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Inoue, M]]
[[Category: Mus musculus]]
[[Category: Kigawa, T]]
[[Category: Inoue M]]
[[Category: Koshiba, S]]
[[Category: Kigawa T]]
[[Category: Li, H]]
[[Category: Koshiba S]]
[[Category: Structural genomic]]
[[Category: Li H]]
[[Category: Tochio, N]]
[[Category: Tochio N]]
[[Category: Yokoyama, S]]
[[Category: Yokoyama S]]
[[Category: Bobby sox homolog]]
[[Category: Hmg_box domain]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rsgi]]
[[Category: Transcription]]
[[Category: Transcription factor]]

Latest revision as of 16:54, 9 May 2024

Solution Structure of the HMG_box Domain of Murine Bobby Sox HomologSolution Structure of the HMG_box Domain of Murine Bobby Sox Homolog

Structural highlights

1wz6 is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

BBX_MOUSE Transcription factor that is necessary for cell cycle progression from G1 to S phase.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Sanchez-Diaz A, Blanco MA, Jones N, Moreno S. HBP2: a new mammalian protein that complements the fission yeast MBF transcription complex. Curr Genet. 2001 Sep;40(2):110-8. PMID:11680820
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