1wg5: Difference between revisions

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==Solution structure of the first RRM domain in heterogeneous nuclear ribonucleoprotein H==
==Solution structure of the first RRM domain in heterogeneous nuclear ribonucleoprotein H==
<StructureSection load='1wg5' size='340' side='right' caption='[[1wg5]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1wg5' size='340' side='right'caption='[[1wg5]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1wg5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WG5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WG5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1wg5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WG5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WG5 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1wez|1wez]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CBL00922 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wg5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wg5 OCA], [https://pdbe.org/1wg5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wg5 RCSB], [https://www.ebi.ac.uk/pdbsum/1wg5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wg5 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wg5 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wg5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wg5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1wg5 RCSB], [http://www.ebi.ac.uk/pdbsum/1wg5 PDBsum], [http://www.topsan.org/Proteins/RSGI/1wg5 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HNRH2_HUMAN HNRH2_HUMAN]] This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG).  
[https://www.uniprot.org/uniprot/HNRH2_HUMAN HNRH2_HUMAN] This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wg/1wg5_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wg/1wg5_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wg5 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Nucleoprotein|Nucleoprotein]]
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: He, F]]
[[Category: Large Structures]]
[[Category: Inoue, M]]
[[Category: He F]]
[[Category: Kigawa, T]]
[[Category: Inoue M]]
[[Category: Muto, Y]]
[[Category: Kigawa T]]
[[Category: Structural genomic]]
[[Category: Muto Y]]
[[Category: Shirouzu, M]]
[[Category: Shirouzu M]]
[[Category: Terada, T]]
[[Category: Terada T]]
[[Category: Yokoyama, S]]
[[Category: Yokoyama S]]
[[Category: Heterogeneous nuclear ribonucleoprotein h]]
[[Category: Rna binding protein]]
[[Category: Rrm domain]]
[[Category: Rsgi]]

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