1wg5: Difference between revisions

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[[Image:1wg5.png|left|200px]]


{{STRUCTURE_1wg5|  PDB=1wg5  |  SCENE=  }}
==Solution structure of the first RRM domain in heterogeneous nuclear ribonucleoprotein H==
 
<StructureSection load='1wg5' size='340' side='right'caption='[[1wg5]]' scene=''>
===Solution structure of the first RRM domain in heterogeneous nuclear ribonucleoprotein H===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1wg5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WG5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WG5 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wg5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wg5 OCA], [https://pdbe.org/1wg5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wg5 RCSB], [https://www.ebi.ac.uk/pdbsum/1wg5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wg5 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wg5 TOPSAN]</span></td></tr>
[[1wg5]] is a 1 chain structure of [[Nucleoprotein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WG5 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/HNRH2_HUMAN HNRH2_HUMAN] This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wg/1wg5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wg5 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Nucleoprotein|Nucleoprotein]]
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: He, F.]]
[[Category: Large Structures]]
[[Category: Inoue, M.]]
[[Category: He F]]
[[Category: Kigawa, T.]]
[[Category: Inoue M]]
[[Category: Muto, Y.]]
[[Category: Kigawa T]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Muto Y]]
[[Category: Shirouzu, M.]]
[[Category: Shirouzu M]]
[[Category: Terada, T.]]
[[Category: Terada T]]
[[Category: Yokoyama, S.]]
[[Category: Yokoyama S]]
[[Category: Heterogeneous nuclear ribonucleoprotein h]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rna binding protein]]
[[Category: Rrm domain]]
[[Category: Rsgi]]
[[Category: Structural genomic]]

Latest revision as of 16:37, 9 May 2024

Solution structure of the first RRM domain in heterogeneous nuclear ribonucleoprotein HSolution structure of the first RRM domain in heterogeneous nuclear ribonucleoprotein H

Structural highlights

1wg5 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

HNRH2_HUMAN This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

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