1wf7: Difference between revisions

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-[[Image:1wf7.jpg|left|200px]]
- {{Structure
+==Solution structure of the PDZ domain of Enigma homologue protein==
-|PDB= 1wf7 |SIZE=350|CAPTION= <scene name='initialview01'>1wf7</scene>
+<StructureSection load='1wf7' size='340' side='right'caption='[[1wf7]]' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND=
+<table><tr><td colspan='2'>[[1wf7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WF7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WF7 FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-|GENE= RIKEN 1110001A05 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wf7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wf7 OCA], [https://pdbe.org/1wf7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wf7 RCSB], [https://www.ebi.ac.uk/pdbsum/1wf7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wf7 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wf7 TOPSAN]</span></td></tr>
-}}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PDLI5_MOUSE PDLI5_MOUSE] May play an important role in the heart development by scaffolding PKC to the Z-disk region. Isoform 2 and isoform 3 may negatively modulate the scaffolding activity of isoform 1. May play a role in the regulation of cardiomyocyte expansion. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May restrain postsynaptic growth of excitatory synapses (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wf/1wf7_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wf7 ConSurf].
+<div style="clear:both"></div>
-'''Solution structure of the PDZ domain of Enigma homologue protein'''
+==See Also==
+*[[PDZ and LIM domain protein|PDZ and LIM domain protein]]
+__TOC__
-==About this Structure==
+</StructureSection>
-WF7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WF7 OCA].
+[[Category: Large Structures]]
 [[Category: Mus musculus]]
-[[Category: Single protein]]
+[[Category: Hayashi F]]
-[[Category: Hayashi, F.]]
+[[Category: Kigawa T]]
-[[Category: Kigawa, T.]]
+[[Category: Qin X]]
-[[Category: Qin, X.]]
+[[Category: Tochio N]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Yokoyama S]]
-[[Category: Tochio, N.]]
-[[Category: Yokoyama, S.]]
-[[Category: enigma homologue protein]]
-[[Category: pdz domain]]
-[[Category: riken structural genomics/proteomics initiative]]
-[[Category: rsgi]]
-[[Category: structural genomic]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:56:11 2008''