8th7: Difference between revisions

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-'''Unreleased structure'''
-The entry 8th7 is ON HOLD
+==Crystal Structure of the G3BP1 NTF2-like domain bound to the Caprin1 peptide==
+<StructureSection load='8th7' size='340' side='right'caption='[[8th7]], [[Resolution|resolution]] 2.88&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8th7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TH7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TH7 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.88&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8th7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8th7 OCA], [https://pdbe.org/8th7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8th7 RCSB], [https://www.ebi.ac.uk/pdbsum/8th7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8th7 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/G3BP1_HUMAN G3BP1_HUMAN] May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.<ref>PMID:9889278</ref> <ref>PMID:11604510</ref>
-Authors: Hughes, M.P., Taylor, J.P.
+==See Also==
+*[[3D structures of G3BP|3D structures of G3BP]]
-Description: Crystal Structure of the G3BP1 NTF2-like domain bound to the Caprin1 peptide
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
-[[Category: Hughes, M.P]]
+__TOC__
-[[Category: Taylor, J.P]]
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Hughes MP]]
+[[Category: Taylor JP]]