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==Electron cryo-microscopy of Cowpea Mosaic Virus (CPMV) empty virus like particle (eVLP)==
==Electron cryo-microscopy of Cowpea Mosaic Virus (CPMV) empty virus like particle (eVLP)==
<StructureSection load='5a33' size='340' side='right' caption='[[5a33]], [[Resolution|resolution]] 3.04&Aring;' scene=''>
<SX load='5a33' size='340' side='right' viewer='molstar' caption='[[5a33]], [[Resolution|resolution]] 3.04&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5a33]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A33 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A33 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5a33]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cowpea_mosaic_virus Cowpea mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A33 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A33 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a32|5a32]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.04&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a33 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a33 OCA], [http://pdbe.org/5a33 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a33 RCSB], [http://www.ebi.ac.uk/pdbsum/5a33 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5a33 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a33 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a33 OCA], [https://pdbe.org/5a33 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a33 RCSB], [https://www.ebi.ac.uk/pdbsum/5a33 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a33 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/POL2_CPMVS POL2_CPMVS]] Movement protein: transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding. The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier. Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids. Binds to GTP and to single-stranded RNA and single-stranded DNA in a non-sequence-specific manner.<ref>PMID:10049828</ref> <ref>PMID:15483261</ref> <ref>PMID:15165817</ref> <ref>PMID:14722313</ref>  The cleavable C-terminus of small coat protein seems to be involved in the packaging of the virion RNAs. Also seems to act as suppressor of post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.<ref>PMID:10049828</ref> <ref>PMID:15483261</ref> <ref>PMID:15165817</ref> <ref>PMID:14722313</ref>
[https://www.uniprot.org/uniprot/POL2_CPMVS POL2_CPMVS] Movement protein: transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding. The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier. Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids. Binds to GTP and to single-stranded RNA and single-stranded DNA in a non-sequence-specific manner.<ref>PMID:10049828</ref> <ref>PMID:15483261</ref> <ref>PMID:15165817</ref> <ref>PMID:14722313</ref>  The cleavable C-terminus of small coat protein seems to be involved in the packaging of the virion RNAs. Also seems to act as suppressor of post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.<ref>PMID:10049828</ref> <ref>PMID:15483261</ref> <ref>PMID:15165817</ref> <ref>PMID:14722313</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5a33" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5a33" style="background-color:#fffaf0;"></div>
==See Also==
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</SX>
[[Category: Cockburn, J J]]
[[Category: Cowpea mosaic virus]]
[[Category: Dent, K C]]
[[Category: Large Structures]]
[[Category: Hesketh, E L]]
[[Category: Cockburn JJ]]
[[Category: Lomonossoff, G P]]
[[Category: Dent KC]]
[[Category: Meshcheriakova, Y]]
[[Category: Hesketh EL]]
[[Category: Ranson, N A]]
[[Category: Lomonossoff GP]]
[[Category: Saxena, P]]
[[Category: Meshcheriakova Y]]
[[Category: Thompson, R]]
[[Category: Ranson NA]]
[[Category: Comoviridae]]
[[Category: Saxena P]]
[[Category: Cpmv]]
[[Category: Thompson R]]
[[Category: Evlp]]
[[Category: Picornavirales]]
[[Category: Virus]]

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