4zqh: Difference between revisions

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 ==Crystal structure of DOX-P Reductoisomerase in complex with NADPH, fosmidomycin and magnesium==
-<StructureSection load='4zqh' size='340' side='right' caption='[[4zqh]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+<StructureSection load='4zqh' size='340' side='right'caption='[[4zqh]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4zqh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZQH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZQH FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4zqh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Moraxella_catarrhalis Moraxella catarrhalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZQH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZQH FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FOM:3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC+ACID'>FOM</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/1-deoxy-D-xylulose-5-phosphate_reductoisomerase 1-deoxy-D-xylulose-5-phosphate reductoisomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.267 1.1.1.267] </span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FOM:3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC+ACID'>FOM</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zqh OCA], [http://pdbe.org/4zqh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zqh RCSB], [http://www.ebi.ac.uk/pdbsum/4zqh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zqh ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zqh OCA], [https://pdbe.org/4zqh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zqh RCSB], [https://www.ebi.ac.uk/pdbsum/4zqh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zqh ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/D5VAW2_MORCB D5VAW2_MORCB] Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).[HAMAP-Rule:MF_00183]
+==See Also==
+*[[DXP reductoisomerase 3D Structures|DXP reductoisomerase 3D Structures]]
 __TOC__
 </StructureSection>
-[[Category: 1-deoxy-D-xylulose-5-phosphate reductoisomerase]]
+[[Category: Large Structures]]
-[[Category: Birkinshaw, R W]]
+[[Category: Moraxella catarrhalis]]
-[[Category: Brady, R L]]
+[[Category: Birkinshaw RW]]
-[[Category: Fosmidomycin]]
+[[Category: Brady RL]]
-[[Category: Mep pathway]]
-[[Category: Nadph]]
-[[Category: Oxidoreductase]]
-[[Category: Reductoisomerase]]