4uyh: Difference between revisions

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 ==N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 1-((2R,4S)-2-methyl-4-(phenylamino)-6-(4-(piperidin-1-ylmethyl)phenyl)-3,4-dihydroquinolin-1(2H)-yl)ethanone==
-<StructureSection load='4uyh' size='340' side='right' caption='[[4uyh]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
+<StructureSection load='4uyh' size='340' side='right'caption='[[4uyh]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4uyh]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UYH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UYH FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4uyh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UYH FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9S3:1-[(2S,4R)-2-METHYL-4-(PHENYLAMINO)-6-[4-(PIPERIDIN-1-YLMETHYL)PHENYL]-3,4-DIHYDROQUINOLIN-1(2H)-YL]ETHANONE'>9S3</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uyd|4uyd]], [[4uye|4uye]], [[4uyf|4uyf]], [[4uyg|4uyg]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9S3:1-[(2S,4R)-2-METHYL-4-(PHENYLAMINO)-6-[4-(PIPERIDIN-1-YLMETHYL)PHENYL]-3,4-DIHYDROQUINOLIN-1(2H)-YL]ETHANONE'>9S3</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uyh OCA], [http://pdbe.org/4uyh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uyh RCSB], [http://www.ebi.ac.uk/pdbsum/4uyh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uyh ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uyh OCA], [https://pdbe.org/4uyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uyh RCSB], [https://www.ebi.ac.uk/pdbsum/4uyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uyh ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN]] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref>
+[https://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
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 ==See Also==
-*[[Bromodomain-containing protein|Bromodomain-containing protein]]
+*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Bamborough, P]]
+[[Category: Homo sapiens]]
-[[Category: Chung, C]]
+[[Category: Large Structures]]
-[[Category: Gosmini, R]]
+[[Category: Bamborough P]]
-[[Category: Bet]]
+[[Category: Chung C]]
-[[Category: Brd2]]
+[[Category: Gosmini R]]
-[[Category: Bromodomain]]
-[[Category: Epigenetic reader]]
-[[Category: Histone]]
-[[Category: Transcription]]