4uct: Difference between revisions
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New page: '''Unreleased structure''' The entry 4uct is ON HOLD Authors: Hale, M., Brassington, C., Carcanague, D., Embrey, K., Eyermann, C.J., Giacobbe, R.A., Gingipali, L., Gowravaram, M., Haran... |
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==Fragment bound to H.influenza NAD dependent DNA ligase== | |||
<StructureSection load='4uct' size='340' side='right'caption='[[4uct]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4uct]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UCT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UCT FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5U1:2-AMINO-6-METHYL-5-(PROPAN-2-YLOXY)-3H-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-8-IUM'>5U1</scene>, <scene name='pdbligand=IWH:1-(2,4-DIMETHYLBENZYL)-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXAMIDE'>IWH</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uct FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uct OCA], [https://pdbe.org/4uct PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uct RCSB], [https://www.ebi.ac.uk/pdbsum/4uct PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uct ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DNLJ_HAEIN DNLJ_HAEIN] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity). | |||
==See Also== | |||
*[[DNA ligase 3D structures|DNA ligase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Haemophilus influenzae]] | |||
[[Category: Large Structures]] | |||
[[Category: Boriack-Sjodin PA]] | |||
[[Category: Brassington C]] | |||
[[Category: Carcanague D]] | |||
[[Category: Embrey K]] | |||
[[Category: Eyermann CJ]] | |||
[[Category: Giacobbe RA]] | |||
[[Category: Gingipali L]] | |||
[[Category: Gowravaram M]] | |||
[[Category: Hale M]] | |||
[[Category: Harang J]] | |||
[[Category: Howard T]] | |||
[[Category: Ioannidis G]] | |||
[[Category: Jahic H]] | |||
[[Category: Kutschke A]] | |||
[[Category: Laganas VA]] | |||
[[Category: Loch J]] | |||
[[Category: Miller MD]] | |||
[[Category: Murphy-Benenato KE]] | |||
[[Category: Oguto H]] | |||
[[Category: Otterbein L]] | |||
[[Category: Patel SJ]] | |||
[[Category: Shapiro AB]] | |||
Latest revision as of 14:19, 9 May 2024
Fragment bound to H.influenza NAD dependent DNA ligaseFragment bound to H.influenza NAD dependent DNA ligase
Structural highlights
FunctionDNLJ_HAEIN DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity). See Also |
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