4cyp: Difference between revisions
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==Leishmania major N-myristoyltransferase in complex with a pyrrolidine inhibitor.== | ==Leishmania major N-myristoyltransferase in complex with a pyrrolidine inhibitor.== | ||
<StructureSection load='4cyp' size='340' side='right' caption='[[4cyp]], [[Resolution|resolution]] 1.55Å' scene=''> | <StructureSection load='4cyp' size='340' side='right'caption='[[4cyp]], [[Resolution|resolution]] 1.55Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4cyp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CYP OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[4cyp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CYP FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A62:(3R)-4-(4-CHLOROPHENYL)-1-[(3S,4R)-3-(4-CHLOROPHENYL)-4-(HYDROXYMETHYL)PYRROLIDIN-1-YL]-3-HYDROXYBUTAN-1-ONE'>A62</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A62:(3R)-4-(4-CHLOROPHENYL)-1-[(3S,4R)-3-(4-CHLOROPHENYL)-4-(HYDROXYMETHYL)PYRROLIDIN-1-YL]-3-HYDROXYBUTAN-1-ONE'>A62</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cyp OCA], [https://pdbe.org/4cyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cyp RCSB], [https://www.ebi.ac.uk/pdbsum/4cyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cyp ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/Q4Q5S8_LEIMA Q4Q5S8_LEIMA] Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins (By similarity). | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4cyp" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Bell | [[Category: Leishmania major]] | ||
[[Category: Brannigan | [[Category: Bell AS]] | ||
[[Category: Goncalves | [[Category: Brannigan JA]] | ||
[[Category: Hutton | [[Category: Goncalves V]] | ||
[[Category: Leatherbarrow | [[Category: Hutton JA]] | ||
[[Category: Paape | [[Category: Leatherbarrow RJ]] | ||
[[Category: Roberts | [[Category: Paape D]] | ||
[[Category: Smith | [[Category: Roberts SM]] | ||
[[Category: Tate | [[Category: Smith DF]] | ||
[[Category: Waugh | [[Category: Tate EW]] | ||
[[Category: Wilkinson | [[Category: Waugh T]] | ||
[[Category: Wilkinson AJ]] | |||