4ce7: Difference between revisions

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 ==Crystal structure of a novel unsaturated beta-glucuronyl hydrolase enzyme, belonging to family GH105, involved in ulvan degradation==
-<StructureSection load='4ce7' size='340' side='right' caption='[[4ce7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
+<StructureSection load='4ce7' size='340' side='right'caption='[[4ce7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4ce7]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Cip_110082 Cip 110082]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CE7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CE7 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4ce7]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Nonlabens_ulvanivorans Nonlabens ulvanivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CE7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CE7 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Unsaturated_rhamnogalacturonyl_hydrolase Unsaturated rhamnogalacturonyl hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.172 3.2.1.172] </span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ce7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ce7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ce7 RCSB], [http://www.ebi.ac.uk/pdbsum/4ce7 PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ce7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ce7 OCA], [https://pdbe.org/4ce7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ce7 RCSB], [https://www.ebi.ac.uk/pdbsum/4ce7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ce7 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/UH105_NONUL UH105_NONUL] Glucuronyl hydrolase involved in ulvan degradation. Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl). Unsaturated 3S-rhamnoglycuronyl hydrolase works together with ulvan lyases to fully degrade the ulvan polymer, catalyzing specifically the cleavage of the unsaturated 4-deoxy-L-threo-hex-4-enopyranosiduronic acid (deltaUA) of deltaUA-Rha3S disaccharides and deltaUA-Rha3S-Xyl-Rha3S tetrasaccharides, the end products of the ulvan lyase reaction. Also hydrolases deltaUA-Rha3S-IduA-Rha3S and deltaUA-Rha3S-GlcA-Rha3S tetrasaccharidestetrasaccharides. Prefers tetrasaccharides over disaccharides and prefers an uronic residue at subsite +2.<ref>PMID:24407291</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
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 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 4ce7" style="background-color:#fffaf0;"></div>
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Cip 110082]]
+[[Category: Large Structures]]
-[[Category: Unsaturated rhamnogalacturonyl hydrolase]]
+[[Category: Nonlabens ulvanivorans]]
-[[Category: Collen, P Nyvall]]
+[[Category: Coutinho PM]]
-[[Category: Coutinho, P M]]
+[[Category: Czjzek M]]
-[[Category: Czjzek, M]]
+[[Category: Groisillier A]]
-[[Category: Groisillier, A]]
+[[Category: Helbert W]]
-[[Category: Helbert, W]]
+[[Category: Jeudy A]]
-[[Category: Jeudy, A]]
+[[Category: Nyvall Collen P]]
-[[Category: Exo-enzyme]]
-[[Category: Family gh105]]
-[[Category: Hydrolase]]
-[[Category: Marine polysaccharide]]
-[[Category: Ulvan degradation]]