4a8k: Difference between revisions

No edit summary
No edit summary
 
(4 intermediate revisions by the same user not shown)
Line 1: Line 1:
==Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation==
==Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation==
<StructureSection load='4a8k' size='340' side='right' caption='[[4a8k]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
<StructureSection load='4a8k' size='340' side='right'caption='[[4a8k]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4a8k]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_phage_phi6 Pseudomonas phage phi6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A8K FirstGlance]. <br>
<table><tr><td colspan='2'>[[4a8k]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_virus_phi6 Pseudomonas virus phi6] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A8K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A8K FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jlg|2jlg]], [[1uvn|1uvn]], [[1uvj|1uvj]], [[1hht|1hht]], [[2jl9|2jl9]], [[2jlf|2jlf]], [[1hi1|1hi1]], [[1uvm|1uvm]], [[1wac|1wac]], [[1uvk|1uvk]], [[1hhs|1hhs]], [[1hi0|1hi0]], [[1uvi|1uvi]], [[1uvl|1uvl]], [[1hi8|1hi8]], [[4a8f|4a8f]], [[4a8m|4a8m]], [[4a8o|4a8o]], [[4a8q|4a8q]], [[4a8w|4a8w]], [[4a8s|4a8s]], [[4a8y|4a8y]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a8k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a8k OCA], [https://pdbe.org/4a8k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a8k RCSB], [https://www.ebi.ac.uk/pdbsum/4a8k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a8k ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a8k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a8k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a8k RCSB], [http://www.ebi.ac.uk/pdbsum/4a8k PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/RDRP_BPPH6 RDRP_BPPH6]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 14: Line 16:
Noncatalytic ions direct the RNA-dependent RNA polymerase of bacterial double-stranded RNA virus varphi6 from de novo initiation to elongation.,Wright S, Poranen MM, Bamford DH, Stuart DI, Grimes JM J Virol. 2012 Mar;86(5):2837-49. Epub 2011 Dec 28. PMID:22205747<ref>PMID:22205747</ref>
Noncatalytic ions direct the RNA-dependent RNA polymerase of bacterial double-stranded RNA virus varphi6 from de novo initiation to elongation.,Wright S, Poranen MM, Bamford DH, Stuart DI, Grimes JM J Virol. 2012 Mar;86(5):2837-49. Epub 2011 Dec 28. PMID:22205747<ref>PMID:22205747</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4a8k" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[RNA polymerase|RNA polymerase]]
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pseudomonas phage phi6]]
[[Category: Large Structures]]
[[Category: RNA-directed RNA polymerase]]
[[Category: Pseudomonas virus phi6]]
[[Category: Bamford, D H.]]
[[Category: Synthetic construct]]
[[Category: Grimes, J M.]]
[[Category: Bamford DH]]
[[Category: Poranen, M M.]]
[[Category: Grimes JM]]
[[Category: Stuart, D I.]]
[[Category: Poranen MM]]
[[Category: Wright, S.]]
[[Category: Stuart DI]]
[[Category: Transferase]]
[[Category: Wright S]]
[[Category: Transferase-dna complex]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA