2xqa: Difference between revisions
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==Pentameric ligand gated ion channel GLIC in complex with tetrabutylantimony (TBSb)== | ==Pentameric ligand gated ion channel GLIC in complex with tetrabutylantimony (TBSb)== | ||
<StructureSection load='2xqa' size='340' side='right' caption='[[2xqa]], [[Resolution|resolution]] 3.70Å' scene=''> | <StructureSection load='2xqa' size='340' side='right'caption='[[2xqa]], [[Resolution|resolution]] 3.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2xqa]] is a 5 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2xqa]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Gloeobacter_violaceus_PCC_7421 Gloeobacter violaceus PCC 7421]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XQA FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.7Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SB:ANTIMONY+(III)+ION'>SB</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xqa OCA], [https://pdbe.org/2xqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xqa RCSB], [https://www.ebi.ac.uk/pdbsum/2xqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xqa ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Ion channels|Ion channels]] | *[[Ion channels 3D structures|Ion channels 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Gloeobacter violaceus PCC 7421]] | ||
[[Category: Bertozzi | [[Category: Large Structures]] | ||
[[Category: Dutzler | [[Category: Bertozzi C]] | ||
[[Category: Hilf | [[Category: Dutzler R]] | ||
[[Category: Reiter | [[Category: Hilf RJC]] | ||
[[Category: Trauner | [[Category: Reiter A]] | ||
[[Category: Zimmermann | [[Category: Trauner D]] | ||
[[Category: Zimmermann I]] | |||