2xq5: Difference between revisions

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-==PENTAMERIC LIGAND GATED ION CHANNEL GLIC IN COMPLEX WITH TETRAETHYLARSONIUM (TEAS)==
-<StructureSection load='2xq5' size='340' side='right' caption='[[2xq5]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
+==Pentameric ligand gated ion channel GLIC in complex with tetraethylarsonium (TEAs)==
+<StructureSection load='2xq5' size='340' side='right'caption='[[2xq5]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2xq5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Gloeobacter_violaceus_pcc_7421 Gloeobacter violaceus pcc 7421]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XQ5 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2xq5]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Gloeobacter_violaceus_PCC_7421 Gloeobacter violaceus PCC 7421]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XQ5 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xqa|2xqa]], [[2xq9|2xq9]], [[2xq7|2xq7]], [[2xq3|2xq3]], [[2xq8|2xq8]], [[2xq4|2xq4]], [[2xq6|2xq6]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xq5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xq5 RCSB], [http://www.ebi.ac.uk/pdbsum/2xq5 PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xq5 OCA], [https://pdbe.org/2xq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xq5 RCSB], [https://www.ebi.ac.uk/pdbsum/2xq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xq5 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 15: / Line 18: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 2xq5" style="background-color:#fffaf0;"></div>
 ==See Also==
-*[[Ion channels|Ion channels]]
+*[[Ion channels 3D structures|Ion channels 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Gloeobacter violaceus pcc 7421]]
+[[Category: Gloeobacter violaceus PCC 7421]]
-[[Category: Bertozzi, C.]]
+[[Category: Large Structures]]
-[[Category: Dutzler, R.]]
+[[Category: Bertozzi C]]
-[[Category: Hilf, R J.C.]]
+[[Category: Dutzler R]]
-[[Category: Reiter, A.]]
+[[Category: Hilf RJC]]
-[[Category: Trauner, D.]]
+[[Category: Reiter A]]
-[[Category: Zimmermann, I.]]
+[[Category: Trauner D]]
-[[Category: Membrane protein]]
+[[Category: Zimmermann I]]
-[[Category: Open channel block]]