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==CRYOEM MODEL OF THE VESICULAR STOMATITIS VIRUS== | ==CRYOEM MODEL OF THE VESICULAR STOMATITIS VIRUS== | ||
< | <SX load='2wyy' size='340' side='right' viewer='molstar' caption='[[2wyy]], [[Resolution|resolution]] 10.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2wyy]] is a 12 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2wyy]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Vesicular_stomatitis_Indiana_virus_strain_San_Juan Vesicular stomatitis Indiana virus strain San Juan]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WYY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WYY FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 10Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wyy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wyy OCA], [https://pdbe.org/2wyy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wyy RCSB], [https://www.ebi.ac.uk/pdbsum/2wyy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wyy ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/NCAP_VSIVA NCAP_VSIVA] Encapsidates the genome in a ratio of one N per nine ribonucleotides, protecting it from nucleases. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. Replication is dependent on intracellular concentration of newly synthesized N, termed N(0), which corresponds to the protein not associated with RNA. In contrast, when associated with RNA, it is termed N. During replication, encapsidation by N(0) is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wy/2wyy_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wy/2wyy_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 29: | Line 30: | ||
==See Also== | ==See Also== | ||
*[[Nucleoprotein|Nucleoprotein]] | *[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</ | </SX> | ||
[[Category: Vesicular stomatitis | [[Category: Large Structures]] | ||
[[Category: Ge | [[Category: Vesicular stomatitis Indiana virus strain San Juan]] | ||
[[Category: Green | [[Category: Ge P]] | ||
[[Category: Luo | [[Category: Green TJ]] | ||
[[Category: Tsao | [[Category: Luo M]] | ||
[[Category: Zhou | [[Category: Tsao J]] | ||
[[Category: Zhou ZH]] | |||
Latest revision as of 13:19, 9 May 2024
CRYOEM MODEL OF THE VESICULAR STOMATITIS VIRUSCRYOEM MODEL OF THE VESICULAR STOMATITIS VIRUS
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