2wjr: Difference between revisions

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==NanC porin structure in rhombohedral crystal form.==
==NanC porin structure in rhombohedral crystal form.==
<StructureSection load='2wjr' size='340' side='right' caption='[[2wjr]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='2wjr' size='340' side='right'caption='[[2wjr]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wjr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WJR FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wjr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WJR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=OCT:N-OCTANE'>OCT</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wjq|2wjq]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=OCT:N-OCTANE'>OCT</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wjr OCA], [http://pdbe.org/2wjr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wjr RCSB], [http://www.ebi.ac.uk/pdbsum/2wjr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wjr ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wjr OCA], [https://pdbe.org/2wjr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wjr RCSB], [https://www.ebi.ac.uk/pdbsum/2wjr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wjr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NANC_ECOLI NANC_ECOLI]] Outer membrane channel protein allowing the entry of N-acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria (Probable). NanC proteins form high-conductance channels which are open at low membrane potentials and which have a weak anion selectivity.<ref>PMID:15743943</ref>
[https://www.uniprot.org/uniprot/NANC_ECOLI NANC_ECOLI] Outer membrane channel protein allowing the entry of N-acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria (Probable). NanC proteins form high-conductance channels which are open at low membrane potentials and which have a weak anion selectivity.<ref>PMID:15743943</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Condemine, G]]
[[Category: Large Structures]]
[[Category: Peneff, C M]]
[[Category: Condemine G]]
[[Category: Schirmer, T]]
[[Category: Peneff CM]]
[[Category: Wirth, C]]
[[Category: Schirmer T]]
[[Category: Beta-barrel]]
[[Category: Wirth C]]
[[Category: Carbohydrate transport]]
[[Category: Cell membrane]]
[[Category: Cell outer membrane]]
[[Category: Ion transport]]
[[Category: Kdgm family]]
[[Category: Membrane]]
[[Category: Membrane protein]]
[[Category: Monomeric porin]]
[[Category: Porin]]
[[Category: Sialic acid translocation]]
[[Category: Sugar transport]]
[[Category: Transmembrane]]
[[Category: Transport]]
[[Category: Transport protein]]

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