2w4u: Difference between revisions

<table><tr><td colspan='2'>[[2w4u]] is a 36 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W4U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W4U FirstGlance]. <br>

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tnq|1tnq]], [[2aso|2aso]], [[1wua|1wua]], [[1o18|1o18]], [[2d1k|2d1k]], [[1ncx|1ncx]], [[1ew7|1ew7]], [[2a5x|2a5x]], [[2v52|2v52]], [[1j6z|1j6z]], [[1npq|1npq]], [[1atn|1atn]], [[1ytz|1ytz]], [[1s22|1s22]], [[1t44|1t44]], [[1zac|1zac]], [[2ff6|2ff6]], [[1o1f|1o1f]], [[2tma|2tma]], [[1blq|1blq]], [[1jc2|1jc2]], [[1o19|1o19]], [[1o1e|1o1e]], [[1p8z|1p8z]], [[1o1c|1o1c]], [[2vcp|2vcp]], [[1o1g|1o1g]], [[1vdi|1vdi]], [[1qz6|1qz6]], [[1avs|1avs]], [[1lcu|1lcu]], [[2a42|2a42]], [[1top|1top]], [[1ijj|1ijj]], [[1o1a|1o1a]], [[1tnx|1tnx]], [[1m8q|1m8q]], [[1uy5|1uy5]], [[1rfq|1rfq]], [[1ma9|1ma9]], [[1rdw|1rdw]], [[1o1b|1o1b]], [[1o1d|1o1d]], [[1ncy|1ncy]], [[2a40|2a40]], [[1qz5|1qz5]], [[1nwk|1nwk]], [[1smg|1smg]], [[1sqk|1sqk]], [[1tnp|1tnp]], [[1pon|1pon]], [[1tnw|1tnw]], [[2ff3|2ff3]], [[1mvw|1mvw]], [[1eqy|1eqy]], [[2fxu|2fxu]], [[2v51|2v51]], [[1kxp|1kxp]], [[2asp|2asp]], [[2d3e|2d3e]], [[1rgi|1rgi]], [[1y64|1y64]], [[1ncz|1ncz]], [[1alm|1alm]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w4u OCA], [http://pdbe.org/2w4u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w4u RCSB], [http://www.ebi.ac.uk/pdbsum/2w4u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w4u ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/TPM1_RABIT TPM1_RABIT]] Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. [[http://www.uniprot.org/uniprot/TNNC2_CHICK TNNC2_CHICK]] Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. [[http://www.uniprot.org/uniprot/TNNI2_CHICK TNNI2_CHICK]] Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. [[http://www.uniprot.org/uniprot/TNNT3_CHICK TNNT3_CHICK]] Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. [[http://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.  

*[[Tropomyosin|Tropomyosin]]

*[[Troponin|Troponin]]

[[Category: Franzini-Armstrong, C]]

[[Category: Goldman, Y E]]

[[Category: Liu, J]]

[[Category: Lucaveche, C]]

[[Category: Reedy, M C]]

[[Category: Reedy, M K]]

[[Category: Sasaki, H]]

[[Category: Taylor, K A]]

[[Category: Tregear, R T]]

[[Category: Winkler, H]]

[[Category: Wu, S]]

[[Category: Muscle protein]]