2uxh: Difference between revisions

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<StructureSection load='2uxh' size='340' side='right'caption='[[2uxh]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='2uxh' size='340' side='right'caption='[[2uxh]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2uxh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_fluorescens_putidus"_flugge_1886 "bacillus fluorescens putidus" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXH OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2UXH FirstGlance]. <br>
<table><tr><td colspan='2'>[[2uxh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UXH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=QUE:3,5,7,3,4-PENTAHYDROXYFLAVONE'>QUE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2uxi|2uxi]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=QUE:3,5,7,3,4-PENTAHYDROXYFLAVONE'>QUE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2uxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uxh OCA], [http://pdbe.org/2uxh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2uxh RCSB], [http://www.ebi.ac.uk/pdbsum/2uxh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2uxh ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uxh OCA], [https://pdbe.org/2uxh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uxh RCSB], [https://www.ebi.ac.uk/pdbsum/2uxh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uxh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TTGR_PSEPT TTGR_PSEPT]] Represses expression from the ttgABC operon promoter and its own expression. Binds to a promoter region between the divergently transcribed ttgR and ttgABC genes/operons; in the presence of chloramphenicol or tetracycline this binding no longer occurs and ttgR and ttgABC are derepressed. This suggests that TtgR binds these antibiotics.<ref>PMID:11251828</ref>
[https://www.uniprot.org/uniprot/TTGR_PSEPT TTGR_PSEPT] Represses expression from the ttgABC operon promoter and its own expression. Binds to a promoter region between the divergently transcribed ttgR and ttgABC genes/operons; in the presence of chloramphenicol or tetracycline this binding no longer occurs and ttgR and ttgABC are derepressed. This suggests that TtgR binds these antibiotics.<ref>PMID:11251828</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 2uxh" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2uxh" style="background-color:#fffaf0;"></div>
==See Also==
*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]]
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus fluorescens putidus flugge 1886]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Alguel, Y]]
[[Category: Pseudomonas putida]]
[[Category: Gallegos, M T]]
[[Category: Alguel Y]]
[[Category: Krell, T]]
[[Category: Gallegos M-T]]
[[Category: Meng, C]]
[[Category: Krell T]]
[[Category: Ramos, J L]]
[[Category: Meng C]]
[[Category: Teran, W]]
[[Category: Ramos JL]]
[[Category: Zhang, X]]
[[Category: Teran W]]
[[Category: Dna-binding]]
[[Category: Zhang X]]
[[Category: Tetr family]]
[[Category: Transcription]]

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