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==The structure of bluetongue virus VP4 reveals a multifunctional RNA- capping production-line==
==The structure of bluetongue virus VP4 reveals a multifunctional RNA- capping production-line==
<StructureSection load='2jhc' size='340' side='right' caption='[[2jhc]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='2jhc' size='340' side='right'caption='[[2jhc]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2jhc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JHC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JHC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2jhc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bluetongue_virus_(serotype_10_/_American_isolate) Bluetongue virus (serotype 10 / American isolate)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JHC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GUN:GUANINE'>GUN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jh9|2jh9]], [[2jha|2jha]], [[2jhp|2jhp]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GUN:GUANINE'>GUN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jhc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jhc OCA], [http://pdbe.org/2jhc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jhc RCSB], [http://www.ebi.ac.uk/pdbsum/2jhc PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jhc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jhc OCA], [https://pdbe.org/2jhc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jhc RCSB], [https://www.ebi.ac.uk/pdbsum/2jhc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jhc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/VP4_BTV10 VP4_BTV10]] The VP4 protein is one of the five proteins (with VP1, VP3, VP6 and VP7) which form the inner capsid of the virus.  
[https://www.uniprot.org/uniprot/VP4_BTV10 VP4_BTV10] The VP4 protein is one of the five proteins (with VP1, VP3, VP6 and VP7) which form the inner capsid of the virus.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jh/2jhc_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jh/2jhc_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 2jhc" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2jhc" style="background-color:#fffaf0;"></div>
==See Also==
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Grimes, J M]]
[[Category: Large Structures]]
[[Category: Roy, P]]
[[Category: Grimes JM]]
[[Category: Stuart, D I]]
[[Category: Roy P]]
[[Category: Sutton, G]]
[[Category: Stuart DI]]
[[Category: Core protein]]
[[Category: Sutton G]]
[[Category: Guanylyltransferase]]
[[Category: Methyltransferase]]
[[Category: Viral capping enzyme]]
[[Category: Viral protein]]
[[Category: Virion protein]]

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