2cmp: Difference between revisions

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-[[Image:2cmp.jpg|left|200px]]
- {{Structure
+==crystal structure of the DNA binding domain of G1P SMALL TERMINASE SUBUNIT from bacteriophage SF6==
-|PDB= 2cmp |SIZE=350|CAPTION= <scene name='initialview01'>2cmp</scene>, resolution 1.58&Aring;
+<StructureSection load='2cmp' size='340' side='right'caption='[[2cmp]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND=
+<table><tr><td colspan='2'>[[2cmp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_phage_SF6 Bacillus phage SF6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CMP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CMP FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58&#8491;</td></tr>
-|GENE=
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cmp OCA], [https://pdbe.org/2cmp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cmp RCSB], [https://www.ebi.ac.uk/pdbsum/2cmp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cmp ProSAT]</span></td></tr>
-}}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TERS_BPSF6 TERS_BPSF6]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cm/2cmp_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cmp ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+DNA packaging in tailed bacteriophages and in evolutionarily related herpesviruses is controlled by a viral-encoded terminase. As in a number of other phages, in the Bacillus subtilis bacteriophages SF6 and SPP1 the terminase complex consists of two proteins: G1P and G2P. The crystal structure of the N-terminal DNA-binding domain of the bacteriophage SF6 small terminase subunit G1P is reported. Structural comparison with other DNA-binding proteins allows a general model for the interaction of G1P with the packaging-initiation site to be proposed.
-'''CRYSTAL STRUCTURE OF THE DNA BINDING DOMAIN OF G1P SMALL TERMINASE SUBUNIT FROM BACTERIOPHAGE SF6'''
+The 1.58 A resolution structure of the DNA-binding domain of bacteriophage SF6 small terminase provides new hints on DNA binding.,Benini S, Chechik M, Ortiz Lombardia M, Polier S, Leech A, Shevtsov MB, Alonso JC Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Apr 1;69(Pt 4):376-81., doi: 10.1107/S1744309113004399. Epub 2013 Mar 28. PMID:23545641<ref>PMID:23545641</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 2cmp" style="background-color:#fffaf0;"></div>
-==About this Structure==
+==See Also==
-CMP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Shigella_phage_sfii Shigella phage sfii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CMP OCA].
+*[[Terminase 3D Structures|Terminase 3D Structures]]
-[[Category: Shigella phage sfii]]
+== References ==
-[[Category: Single protein]]
+<references/>
-[[Category: Alonso, J C.]]
+__TOC__
-[[Category: Antson, A A.]]
+</StructureSection>
-[[Category: Benini, S.]]
+[[Category: Bacillus phage SF6]]
-[[Category: Chechik, M.]]
+[[Category: Large Structures]]
-[[Category: Deluchi, D.]]
+[[Category: Alonso JC]]
-[[Category: Ortiz-Lombardia, M.]]
+[[Category: Antson AA]]
-[[Category: Polier, S.]]
+[[Category: Benini S]]
-[[Category: Shevtsov, M B.]]
+[[Category: Chechik M]]
-[[Category: bacteriophage]]
+[[Category: DeLuchi D]]
-[[Category: dna binding domain]]
+[[Category: Ortiz-Lombardia M]]
-[[Category: dna packaging]]
+[[Category: Polier S]]
-[[Category: sf6]]
+[[Category: Shevtsov MB]]
-[[Category: terminase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:17:23 2008''