2cjr: Difference between revisions

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-==CRYSTAL STRUCTURE OF OLIGOMERIZATION DOMAIN OF SARS CORONAVIRUS NUCLEOCAPSID PROTEIN.==
-<StructureSection load='2cjr' size='340' side='right' caption='[[2cjr]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+==Crystal structure of oligomerization domain of SARS coronavirus nucleocapsid protein.==
+<StructureSection load='2cjr' size='340' side='right'caption='[[2cjr]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2cjr]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Sars_coronavirus_tw1 Sars coronavirus tw1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CJR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CJR FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2cjr]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/SARS_coronavirus_TW1 SARS coronavirus TW1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CJR FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ssk|1ssk]], [[1x7q|1x7q]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cjr OCA], [http://pdbe.org/2cjr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cjr RCSB], [http://www.ebi.ac.uk/pdbsum/2cjr PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cjr OCA], [https://pdbe.org/2cjr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cjr RCSB], [https://www.ebi.ac.uk/pdbsum/2cjr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cjr ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/NCAP_SARS NCAP_SARS] Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication (PubMed:17210170). May modulate transforming growth factor-beta signaling by binding host SMAD3 (PubMed:18055455).[HAMAP-Rule:MF_04096]<ref>PMID:17210170</ref> <ref>PMID:18055455</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cj/2cjr_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cj/2cjr_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cjr ConSurf].
 <div style="clear:both"></div>
 <div style="background-color:#fffaf0;">
@@ Line 29: / Line 32: @@
 __TOC__
 </StructureSection>
-[[Category: Sars coronavirus tw1]]
+[[Category: Large Structures]]
-[[Category: Chen, C Y]]
+[[Category: SARS coronavirus TW1]]
-[[Category: Hsiao, C D]]
+[[Category: Chen C-Y]]
-[[Category: Coronavirus]]
+[[Category: Hsiao C-D]]
-[[Category: Nucleocapsid protein]]
-[[Category: Oligomerization domain]]
-[[Category: Sar]]
-[[Category: Viral protein]]