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==Solution structure of Fowlicidin-1, a novel Cathelicidin antimicrobial peptide from chicken==
==Solution structure of Fowlicidin-1, a novel Cathelicidin antimicrobial peptide from chicken==
<StructureSection load='2amn' size='340' side='right' caption='[[2amn]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2amn' size='340' side='right'caption='[[2amn]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2amn]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AMN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AMN FirstGlance]. <br>
<table><tr><td colspan='2'>[[2amn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AMN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AMN FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2amn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2amn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2amn RCSB], [http://www.ebi.ac.uk/pdbsum/2amn PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2amn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2amn OCA], [https://pdbe.org/2amn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2amn RCSB], [https://www.ebi.ac.uk/pdbsum/2amn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2amn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CTHL1_CHICK CTHL1_CHICK]] Binds bacterial lipopolysaccharide (LPS). Has potent antimicrobial activity against Gram-positive and Gram-negative bacteria (in vitro). Has hemolytic activity (in vitro). May play a role in the innate immune response.<ref>PMID:16326712</ref> <ref>PMID:16817888</ref>
[https://www.uniprot.org/uniprot/CTHL1_CHICK CTHL1_CHICK] Binds bacterial lipopolysaccharide (LPS). Has potent antimicrobial activity against Gram-positive and Gram-negative bacteria (in vitro). Has hemolytic activity (in vitro). May play a role in the innate immune response.<ref>PMID:16326712</ref> <ref>PMID:16817888</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2amn" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bommineni, Y R]]
[[Category: Gallus gallus]]
[[Category: Dai, H]]
[[Category: Large Structures]]
[[Category: Prakash, O]]
[[Category: Bommineni YR]]
[[Category: Xiao, Y]]
[[Category: Dai H]]
[[Category: Zhang, G]]
[[Category: Prakash O]]
[[Category: Antimicrobial protein]]
[[Category: Xiao Y]]
[[Category: Linear helix]]
[[Category: Zhang G]]

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