1wbm: Difference between revisions

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[[Image:1wbm.png|left|200px]]


{{STRUCTURE_1wbm|  PDB=1wbm  |  SCENE=  }}
==HIV-1 protease in complex with symmetric inhibitor, BEA450==
 
<StructureSection load='1wbm' size='340' side='right'caption='[[1wbm]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===HIV-1 PROTEASE IN COMPLEX WITH SYMMETRIC INHIBITOR, BEA450===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1wbm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WBM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WBM FirstGlance]. <br>
{{ABSTRACT_PUBMED_11585446}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BLL:(2R,3R,4R,5R)-3,4-DIHYDROXY-N,N-BIS[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]-2,5-BIS(2-PHENYLETHYL)HEXANEDIAMIDE'>BLL</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wbm OCA], [https://pdbe.org/1wbm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wbm RCSB], [https://www.ebi.ac.uk/pdbsum/1wbm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wbm ProSAT]</span></td></tr>
[[1wbm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WBM OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8Q3H0_9HIV1 Q8Q3H0_9HIV1]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wb/1wbm_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wbm ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Lindberg, J.]]
[[Category: Large Structures]]
[[Category: Unge, T.]]
[[Category: Lindberg J]]
[[Category: Aid]]
[[Category: Unge T]]
[[Category: Aspartyl protease]]
[[Category: Dimer]]
[[Category: Hydrolase]]
[[Category: Hydrolase-inhibitor complex]]
[[Category: Hydrolase/hydrolase inhibitor]]
[[Category: Hydrolase/inhibitor]]
[[Category: Protein-inhibitor complex]]

Latest revision as of 12:14, 9 May 2024

HIV-1 protease in complex with symmetric inhibitor, BEA450HIV-1 protease in complex with symmetric inhibitor, BEA450

Structural highlights

1wbm is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q8Q3H0_9HIV1

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1wbm, resolution 2.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA