1okr: Difference between revisions

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-==THREE-DIMENSIONAL STRUCTURE OF S.AUREUS METHICILLIN-RESISTANCE REGULATING TRANSCRIPTIONAL REPRESSOR MECI.==
-<StructureSection load='1okr' size='340' side='right' caption='[[1okr]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+==Three-dimensional structure of S.aureus methicillin-resistance regulating transcriptional repressor MecI.==
+<StructureSection load='1okr' size='340' side='right'caption='[[1okr]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1okr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OKR FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1okr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OKR FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1okr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1okr OCA], [http://pdbe.org/1okr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1okr RCSB], [http://www.ebi.ac.uk/pdbsum/1okr PDBsum]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1okr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1okr OCA], [https://pdbe.org/1okr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1okr RCSB], [https://www.ebi.ac.uk/pdbsum/1okr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1okr ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/MECI_STAAN MECI_STAAN] Transcriptional repressor that constitutively blocks the transcription of the gene for the penicillin-binding protein MecA. Binds palindromic DNA with the sequence 5'-TACA-[AT]-N-TGTA-3'. Regulates genes involved in antibiotic resistance. Binds DNA as a dimer.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ok/1okr_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ok/1okr_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1okr ConSurf].
 <div style="clear:both"></div>
 <div style="background-color:#fffaf0;">
@@ Line 29: / Line 33: @@
 __TOC__
 </StructureSection>
-[[Category: Coll, M]]
+[[Category: Large Structures]]
-[[Category: Garcia-Castellanos, R]]
+[[Category: Staphylococcus aureus]]
-[[Category: Gomis-Ruth, F X]]
+[[Category: Coll M]]
-[[Category: Mallorqui-Fernandez, G]]
+[[Category: Garcia-Castellanos R]]
-[[Category: Marrero, A]]
+[[Category: Gomis-Ruth FX]]
-[[Category: Potempa, J]]
+[[Category: Mallorqui-Fernandez G]]
-[[Category: Bacterial antibiotic resistance]]
+[[Category: Marrero A]]
-[[Category: Dna-binding protein]]
+[[Category: Potempa J]]
-[[Category: Meci protein]]
-[[Category: Transcriptional regulatory element]]
-[[Category: Winged helix protein]]