1tz4: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-{{Seed}}
-[[Image:1tz4.png|left|200px]]
-<!--
+==[hPP19-23]-pNPY bound to DPC Micelles==
-The line below this paragraph, containing "STRUCTURE_1tz4", creates the "Structure Box" on the page.
+<StructureSection load='1tz4' size='340' side='right'caption='[[1tz4]]' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1tz4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TZ4 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-{{STRUCTURE_1tz4|  PDB=1tz4  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tz4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tz4 OCA], [https://pdbe.org/1tz4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tz4 RCSB], [https://www.ebi.ac.uk/pdbsum/1tz4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tz4 ProSAT]</span></td></tr>
+</table>
-===[hPP19-23]-pNPY bound to DPC Micelles===
+== Function ==
+[https://www.uniprot.org/uniprot/NPY_PIG NPY_PIG] NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.[https://www.uniprot.org/uniprot/PAHO_HUMAN PAHO_HUMAN] Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions.  The physiological role for the icosapeptide has not yet been elucidated.
+== Evolutionary Conservation ==
-<!--
+[[Image:Consurf_key_small.gif|200px|right]]
-The line below this paragraph, {{ABSTRACT_PUBMED_15966750}}, adds the Publication Abstract to the page
+Check<jmol>
-(as it appears on PubMed at http://www.pubmed.gov), where 15966750 is the PubMed ID number.
+  <jmolCheckbox>
--->
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tz/1tz4_consurf.spt"</scriptWhenChecked>
-{{ABSTRACT_PUBMED_15966750}}
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-==About this Structure==
+  </jmolCheckbox>
-TZ4 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa_and_homo_sapiens Sus scrofa and homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZ4 OCA].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tz4 ConSurf].
+<div style="clear:both"></div>
-==Reference==
+__TOC__
-<ref group="xtra">PMID:15966750</ref><references group="xtra"/>
+</StructureSection>
-[[Category: Sus scrofa and homo sapiens]]
+[[Category: Homo sapiens]]
-[[Category: Aguilar, M I.]]
+[[Category: Large Structures]]
-[[Category: Beck-Sickinger, A G.]]
+[[Category: Sus scrofa]]
-[[Category: Folkers, G.]]
+[[Category: Aguilar MI]]
-[[Category: Kamimori, H.]]
+[[Category: Beck-Sickinger AG]]
-[[Category: Lerch, M.]]
+[[Category: Folkers G]]
-[[Category: Zerbe, O.]]
+[[Category: Kamimori H]]
-[[Category: Npy-pp chimera]]
+[[Category: Lerch M]]
+[[Category: Zerbe O]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 22:01:26 2009''