1tf9: Difference between revisions

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-[[Image:1tf9.png|left|200px]]
-<!--
+==Streptomyces griseus aminopeptidase complexed with P-Iodo-L-Phenylalanine==
-The line below this paragraph, containing "STRUCTURE_1tf9", creates the "Structure Box" on the page.
+<StructureSection load='1tf9' size='340' side='right'caption='[[1tf9]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1tf9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TF9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TF9 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PHI:IODO-PHENYLALANINE'>PHI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-{{STRUCTURE_1tf9|  PDB=1tf9  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tf9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tf9 OCA], [https://pdbe.org/1tf9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tf9 RCSB], [https://www.ebi.ac.uk/pdbsum/1tf9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tf9 ProSAT]</span></td></tr>
+</table>
-===Streptomyces griseus aminopeptidase complexed with P-Iodo-L-Phenylalanine===
+== Function ==
+[https://www.uniprot.org/uniprot/APX_STRGG APX_STRGG] An exopeptidase specific for larger hydrophobic amino acids (especially leucine), no cleavage occurs if the next residue is proline (PubMed:8444149).<ref>PMID:2503378</ref> <ref>PMID:8444149</ref> <ref>PMID:8665903</ref>
+== Evolutionary Conservation ==
-<!--
+[[Image:Consurf_key_small.gif|200px|right]]
-The line below this paragraph, {{ABSTRACT_PUBMED_15388919}}, adds the Publication Abstract to the page
+Check<jmol>
-(as it appears on PubMed at http://www.pubmed.gov), where 15388919 is the PubMed ID number.
+  <jmolCheckbox>
--->
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tf/1tf9_consurf.spt"</scriptWhenChecked>
-{{ABSTRACT_PUBMED_15388919}}
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-==About this Structure==
+  </jmolCheckbox>
-[[1tf9]] is a 1 chain structure of [[Streptomyces griseus Aminopeptidase (SGAP)]] with sequence from [http://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TF9 OCA].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tf9 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Streptomyces griseus Aminopeptidase (SGAP)]]
+*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
+*[[Streptomyces griseus Aminopeptidase (SGAP)|Streptomyces griseus Aminopeptidase (SGAP)]]
-==Reference==
+== References ==
-<ref group="xtra">PMID:15388919</ref><references group="xtra"/>
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Streptomyces griseus]]
-[[Category: Blumberg, S.]]
+[[Category: Blumberg S]]
-[[Category: Gilboa, R.]]
+[[Category: Gilboa R]]
-[[Category: Reiland, V.]]
+[[Category: Reiland V]]
-[[Category: Schomburg, D.]]
+[[Category: Schomburg D]]
-[[Category: Shoham, G.]]
+[[Category: Shoham G]]
-[[Category: Shoham, Y.]]
+[[Category: Shoham Y]]
-[[Category: Spungin-Bialik, A.]]
+[[Category: Spungin-Bialik A]]
-[[Category: Calcium activation]]
-[[Category: Double-zinc metalloproteinase]]
-[[Category: Hydrolase]]
-[[Category: Protein-inhibitor complex]]