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[[Image:1rfe.gif|left|200px]]


{{Structure
==Crystal structure of conserved hypothetical protein Rv2991 from Mycobacterium tuberculosis==
|PDB= 1rfe |SIZE=350|CAPTION= <scene name='initialview01'>1rfe</scene>, resolution 2.00&Aring;
<StructureSection load='1rfe' size='340' side='right'caption='[[1rfe]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CSX:S-OXY+CYSTEINE'>CSX</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
<table><tr><td colspan='2'>[[1rfe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RFE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RFE FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
|GENE=
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSX:S-OXY+CYSTEINE'>CSX</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam01243 Pyridox_oxidase]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rfe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rfe OCA], [https://pdbe.org/1rfe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rfe RCSB], [https://www.ebi.ac.uk/pdbsum/1rfe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rfe ProSAT], [https://www.topsan.org/Proteins/TBSGC/1rfe TOPSAN]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rfe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rfe OCA], [http://www.ebi.ac.uk/pdbsum/1rfe PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1rfe RCSB]</span>
== Function ==
}}
[https://www.uniprot.org/uniprot/O53240_MYCTU O53240_MYCTU]
 
== Evolutionary Conservation ==
'''Crystal structure of conserved hypothetical protein Rv2991 from Mycobacterium tuberculosis'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rf/1rfe_consurf.spt"</scriptWhenChecked>
1RFE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RFE OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Mycobacterium tuberculosis h37rv]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Single protein]]
  </jmolCheckbox>
[[Category: Alzari, P.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rfe ConSurf].
[[Category: Benini, S.]]
<div style="clear:both"></div>
[[Category: Betton, J M.]]
__TOC__
[[Category: Dodson, G G.]]
</StructureSection>
[[Category: Haouz, A.]]
[[Category: Large Structures]]
[[Category: Proux, F.]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: TBSGC, TB Structural Genomics Consortium.]]
[[Category: Alzari P]]
[[Category: Wilson, K S.]]
[[Category: Benini S]]
[[Category: fmn binding]]
[[Category: Betton JM]]
[[Category: mycobacterium tuberculosis]]
[[Category: Dodson GG]]
[[Category: protein structure initiative]]
[[Category: Haouz A]]
[[Category: psi]]
[[Category: Proux F]]
[[Category: structural genomic]]
[[Category: Wilson KS]]
[[Category: tb]]
[[Category: tb structural genomics consortium]]
[[Category: tbsgc]]
 
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