6axd: Difference between revisions

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-'''Unreleased structure'''
-The entry 6axd is ON HOLD
+==Structures of REV1 UBM2 domain complex with ubiquitin and with the first small-molecule that inhibits the REV1 UBM2-ubiquitin interaction==
+<StructureSection load='6axd' size='340' side='right'caption='[[6axd]]' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6axd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AXD FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6axd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6axd OCA], [https://pdbe.org/6axd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6axd RCSB], [https://www.ebi.ac.uk/pdbsum/6axd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6axd ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/REV1_HUMAN REV1_HUMAN] Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.<ref>PMID:10536157</ref> <ref>PMID:10760286</ref> <ref>PMID:11278384</ref> <ref>PMID:11485998</ref> <ref>PMID:22266823</ref>
-Authors: Fujii, N., Vanarotti, M.
+==See Also==
+*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
-Description: Structures of REV1 UBM2 domain complex with ubiquitin and with the first small-molecule that inhibits the REV1 UBM2-ubiquitin interaction
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
-[[Category: Vanarotti, M]]
+__TOC__
-[[Category: Fujii, N]]
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Fujii N]]
+[[Category: Vanarotti M]]