4ajh: Difference between revisions

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[[Image:4ajh.png|left|200px]]


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==rat LDHA in complex with N-(2-methyl-1,3-benzothiazol-6-yl)-3-ureido- propanamide and 2-(4-bromophenoxy)propanedioic acid==
The line below this paragraph, containing "STRUCTURE_4ajh", creates the "Structure Box" on the page.
<StructureSection load='4ajh' size='340' side='right'caption='[[4ajh]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[4ajh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AJH FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.93&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2B4:2-(4-BROMANYLPHENOXY)PROPANEDIOIC+ACID'>2B4</scene>, <scene name='pdbligand=88S:N-(2-METHYL-1,3-BENZOTHIAZOL-6-YL)-3-UREIDO-PROPANAMIDE'>88S</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
{{STRUCTURE_4ajh|  PDB=4ajh  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ajh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ajh OCA], [https://pdbe.org/4ajh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ajh RCSB], [https://www.ebi.ac.uk/pdbsum/4ajh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ajh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LDHA_RAT LDHA_RAT]


===rat LDHA in complex with N-(2-methyl-1,3-benzothiazol-6-yl)-3-ureido- propanamide and 2-(4-bromophenoxy)propanedioic acid===
==See Also==
 
*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_22417091}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 22417091 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22417091}}
 
==About this Structure==
[[4ajh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJH OCA].
 
==Reference==
<ref group="xtra">PMID:022417091</ref><references group="xtra"/>
[[Category: L-lactate dehydrogenase]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Brassington, C.]]
[[Category: Brassington C]]
[[Category: Davies, G.]]
[[Category: Davies G]]
[[Category: Debreczeni, J.]]
[[Category: Debreczeni J]]
[[Category: Greenwood, R.]]
[[Category: Greenwood R]]
[[Category: Hassall, G.]]
[[Category: Hassall G]]
[[Category: Pearson, S.]]
[[Category: Pearson S]]
[[Category: Tart, J.]]
[[Category: Tart J]]
[[Category: Tucker, J A.]]
[[Category: Tucker JA]]
[[Category: Ward, R.]]
[[Category: Ward R]]
[[Category: Watson, M.]]
[[Category: Watson M]]
[[Category: Fragment based lead generated inhibitor]]
[[Category: Oxidoreductase-inhibitor complex]]

Latest revision as of 10:14, 1 May 2024

rat LDHA in complex with N-(2-methyl-1,3-benzothiazol-6-yl)-3-ureido- propanamide and 2-(4-bromophenoxy)propanedioic acidrat LDHA in complex with N-(2-methyl-1,3-benzothiazol-6-yl)-3-ureido- propanamide and 2-(4-bromophenoxy)propanedioic acid

Structural highlights

4ajh is a 4 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.93Å
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

LDHA_RAT

See Also

4ajh, resolution 1.93Å

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