4a4q: Difference between revisions

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-{{STRUCTURE_4a4q|  PDB=4a4q  |  SCENE=  }}
-===Stereoselective Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Lactam Based HIV-1 Protease Inhibitors===
-{{ABSTRACT_PUBMED_22376008}}
-==About this Structure==
+==Stereoselective Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Lactam Based HIV-1 Protease Inhibitors==
-[[4a4q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aids_virus Aids virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A4Q OCA].
+<StructureSection load='4a4q' size='340' side='right'caption='[[4a4q]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4a4q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus Human immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A4Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A4Q FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UX9:METHYL+[(2S)-1-{2-(2-{(3R,4S)-3-BENZYL-4-HYDROXY-1-[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]-2-OXOPYRROLIDIN-3-YL}ETHYL)-2-[4-(PYRIDIN-4-YL)BENZYL]HYDRAZINYL}-3,3-DIMETHYL-1-OXOBUTAN-2-YL]CARBAMATE'>UX9</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a4q OCA], [https://pdbe.org/4a4q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a4q RCSB], [https://www.ebi.ac.uk/pdbsum/4a4q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a4q ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q8Q3H0_9HIV1 Q8Q3H0_9HIV1]
 ==See Also==
-*[[Virus protease|Virus protease]]
+*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:022376008</ref><references group="xtra"/><references/>
+[[Category: Human immunodeficiency virus]]
-[[Category: Aids virus]]
+[[Category: Large Structures]]
-[[Category: HIV-1 retropepsin]]
+[[Category: Arvela RK]]
-[[Category: Arvela, R K.]]
+[[Category: Joshi AA]]
-[[Category: Joshi, A A.]]
+[[Category: Larhed M]]
-[[Category: Larhed, M.]]
+[[Category: Ohrngren P]]
-[[Category: Ohrngren, P.]]
+[[Category: Persson M]]
-[[Category: Persson, M.]]
+[[Category: Rosenquist A]]
-[[Category: Rosenquist, A.]]
+[[Category: Samuelsson B]]
-[[Category: Samuelsson, B.]]
+[[Category: Trejos A]]
-[[Category: Trejos, A.]]
+[[Category: Unge J]]
-[[Category: Unge, J.]]
+[[Category: Vrang L]]
-[[Category: Vrang, L.]]
+[[Category: Wallberg H]]
-[[Category: Wallberg, H.]]
+[[Category: Wu X]]
-[[Category: Wu, X.]]
-[[Category: Gamma-butyrol-lactam]]
-[[Category: Hydrolase]]
-[[Category: Inhibitor]]