4a4q: Difference between revisions
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New page: '''Unreleased structure''' The entry 4a4q is ON HOLD Authors: Wu, X., Ohrngren, P., Joshi, A.A., Trejos, A., Persson, M., Arvela, R.K., Wallberg, H., Vrang, L., Rosenquist, A., Samuelss... |
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==Stereoselective Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Lactam Based HIV-1 Protease Inhibitors== | |||
<StructureSection load='4a4q' size='340' side='right'caption='[[4a4q]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4a4q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus Human immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A4Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A4Q FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UX9:METHYL+[(2S)-1-{2-(2-{(3R,4S)-3-BENZYL-4-HYDROXY-1-[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]-2-OXOPYRROLIDIN-3-YL}ETHYL)-2-[4-(PYRIDIN-4-YL)BENZYL]HYDRAZINYL}-3,3-DIMETHYL-1-OXOBUTAN-2-YL]CARBAMATE'>UX9</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a4q OCA], [https://pdbe.org/4a4q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a4q RCSB], [https://www.ebi.ac.uk/pdbsum/4a4q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a4q ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q8Q3H0_9HIV1 Q8Q3H0_9HIV1] | |||
==See Also== | |||
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Human immunodeficiency virus]] | |||
[[Category: Large Structures]] | |||
[[Category: Arvela RK]] | |||
[[Category: Joshi AA]] | |||
[[Category: Larhed M]] | |||
[[Category: Ohrngren P]] | |||
[[Category: Persson M]] | |||
[[Category: Rosenquist A]] | |||
[[Category: Samuelsson B]] | |||
[[Category: Trejos A]] | |||
[[Category: Unge J]] | |||
[[Category: Vrang L]] | |||
[[Category: Wallberg H]] | |||
[[Category: Wu X]] | |||
Latest revision as of 10:13, 1 May 2024
Stereoselective Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Lactam Based HIV-1 Protease InhibitorsStereoselective Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Lactam Based HIV-1 Protease Inhibitors
Structural highlights
FunctionSee Also |
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