2y1z: Difference between revisions

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-[[Image:2y1z.png|left|200px]]
-<!--
+==Human alphaB Crystallin ACD R120G==
-The line below this paragraph, containing "STRUCTURE_2y1z", creates the "Structure Box" on the page.
+<StructureSection load='2y1z' size='340' side='right'caption='[[2y1z]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2y1z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y1Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y1Z FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
-{{STRUCTURE_2y1z|  PDB=2y1z  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y1z OCA], [https://pdbe.org/2y1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y1z RCSB], [https://www.ebi.ac.uk/pdbsum/2y1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y1z ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[https://www.uniprot.org/uniprot/CRYAB_HUMAN CRYAB_HUMAN] Posterior polar cataract;Alpha-crystallinopathy;Zonular cataract;Familial isolated dilated cardiomyopathy;Fatal infantile hypertonic myofibrillar myopathy. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[https://www.uniprot.org/uniprot/CRYAB_HUMAN CRYAB_HUMAN] May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
-===HUMAN ALPHAB CRYSTALLIN ACD R120G===
+==See Also==
+*[[Crystallin 3D structures|Crystallin 3D structures]]
+*[[Multiple sclerosis|Multiple sclerosis]]
-<!--
+__TOC__
-The line below this paragraph, {{ABSTRACT_PUBMED_21329698}}, adds the Publication Abstract to the page
+</StructureSection>
-(as it appears on PubMed at http://www.pubmed.gov), where 21329698 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_21329698}}
-==About this Structure==
-[[2y1z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y1Z OCA].
-==Reference==
-<ref group="xtra">PMID:21329698</ref><ref group="xtra">PMID:19646995</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Bagneris, C.]]
+[[Category: Large Structures]]
-[[Category: Clark, A R.]]
+[[Category: Bagneris C]]
-[[Category: Keep, N H.]]
+[[Category: Clark AR]]
-[[Category: Naylor, C E.]]
+[[Category: Keep NH]]
-[[Category: Slingsby, C.]]
+[[Category: Naylor CE]]
+[[Category: Slingsby C]]