2wcw: Difference between revisions

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[[Image:2wcw.jpg|left|200px]]


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==1.6A resolution structure of Archaeoglobus fulgidus Hjc, a Holliday junction resolvase from an archaeal hyperthermophile==
The line below this paragraph, containing "STRUCTURE_2wcw", creates the "Structure Box" on the page.
<StructureSection load='2wcw' size='340' side='right'caption='[[2wcw]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2wcw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WCW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WCW FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>
{{STRUCTURE_2wcw| PDB=2wcw |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wcw OCA], [https://pdbe.org/2wcw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wcw RCSB], [https://www.ebi.ac.uk/pdbsum/2wcw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wcw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HJC_ARCFU HJC_ARCFU] A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.[HAMAP-Rule:MF_01490]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wc/2wcw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wcw ConSurf].
<div style="clear:both"></div>


===1.6A RESOLUTION STRUCTURE OF ARCHAEOGLOBUS FULGIDUS HJC, A HOLLIDAY JUNCTION RESOLVASE FROM AN ARCHAEAL HYPERTHERMOPHILE===
==See Also==
 
*[[Resolvase 3D structures|Resolvase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2WCW is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WCW OCA].
[[Category: Archaeoglobus fulgidus]]
[[Category: Archaeoglobus fulgidus]]
[[Category: Basquin, J.]]
[[Category: Large Structures]]
[[Category: Carolis, C.]]
[[Category: Basquin J]]
[[Category: Koehler, C.]]
[[Category: Carolis C]]
[[Category: Sauter, C.]]
[[Category: Koehler C]]
[[Category: Suck, D.]]
[[Category: Sauter C]]
[[Category: Toeroe, I.]]
[[Category: Suck D]]
[[Category: Dna binding protein]]
[[Category: Toeroe I]]
[[Category: Holliday junction resolvase]]
[[Category: Hydrolase]]
[[Category: Type ii restriction endonuclease]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 25 12:17:19 2009''

Latest revision as of 10:09, 1 May 2024

1.6A resolution structure of Archaeoglobus fulgidus Hjc, a Holliday junction resolvase from an archaeal hyperthermophile1.6A resolution structure of Archaeoglobus fulgidus Hjc, a Holliday junction resolvase from an archaeal hyperthermophile

Structural highlights

2wcw is a 4 chain structure with sequence from Archaeoglobus fulgidus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.58Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HJC_ARCFU A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.[HAMAP-Rule:MF_01490]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2wcw, resolution 1.58Å

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