2mjg: Difference between revisions

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==Solution Structure of C-terminal AbrB==
==Solution Structure of C-terminal AbrB==
<StructureSection load='2mjg' size='340' side='right' caption='[[2mjg]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='2mjg' size='340' side='right'caption='[[2mjg]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2mjg]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MJG FirstGlance]. <br>
<table><tr><td colspan='2'>[[2mjg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MJG FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mjg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mjg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mjg RCSB], [http://www.ebi.ac.uk/pdbsum/2mjg PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mjg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mjg OCA], [https://pdbe.org/2mjg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mjg RCSB], [https://www.ebi.ac.uk/pdbsum/2mjg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mjg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ABRB_BACSU ABRB_BACSU]] Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription.<ref>PMID:2504584</ref>
[https://www.uniprot.org/uniprot/ABRB_BACSU ABRB_BACSU] Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription.<ref>PMID:2504584</ref>  
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cavanagh, J]]
[[Category: Bacillus subtilis subsp. subtilis str. 168]]
[[Category: Olson, A L]]
[[Category: Large Structures]]
[[Category: Thompson, R J]]
[[Category: Cavanagh J]]
[[Category: Tucker, A T]]
[[Category: Olson AL]]
[[Category: Abrb]]
[[Category: Thompson RJ]]
[[Category: C-terminus]]
[[Category: Tucker AT]]
[[Category: Transcription]]

Latest revision as of 10:00, 1 May 2024

Solution Structure of C-terminal AbrBSolution Structure of C-terminal AbrB

Structural highlights

2mjg is a 2 chain structure with sequence from Bacillus subtilis subsp. subtilis str. 168. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ABRB_BACSU Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription.[1]

References

  1. Strauch MA, Spiegelman GB, Perego M, Johnson WC, Burbulys D, Hoch JA. The transition state transcription regulator abrB of Bacillus subtilis is a DNA binding protein. EMBO J. 1989 May;8(5):1615-21. PMID:2504584
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