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==Pre-Fusion Solution NMR Structure of Neuronal SNARE Syntaxin 1A== | |||
<StructureSection load='2m8r' size='340' side='right'caption='[[2m8r]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2m8r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. The November 2013 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''SNARE Proteins'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2013_11 10.2210/rcsb_pdb/mom_2013_11]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M8R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M8R FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m8r OCA], [https://pdbe.org/2m8r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m8r RCSB], [https://www.ebi.ac.uk/pdbsum/2m8r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m8r ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/STX1A_RAT STX1A_RAT] Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. | |||
==See Also== | |||
*[[Syntaxin 3D structures|Syntaxin 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: RCSB PDB Molecule of the Month]] | |||
[[Category: Rattus norvegicus]] | |||
[[Category: SNARE Proteins]] | |||
[[Category: Kiessling V]] | |||
[[Category: Liang B]] | |||
[[Category: Tamm LK]] | |||
Latest revision as of 09:59, 1 May 2024
Pre-Fusion Solution NMR Structure of Neuronal SNARE Syntaxin 1APre-Fusion Solution NMR Structure of Neuronal SNARE Syntaxin 1A
Structural highlights
FunctionSTX1A_RAT Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. See Also |
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